What is the Difference Between Angiotensin 1 and 2?

Angiotensin I and Angiotensin II are two forms of angiotensins, which are proteins involved in the regulation of blood pressure and fluid balance in the body. The key differences between Angiotensin I and Angiotensin II are:

1. Biological Activity: Angiotensin I is an inactive form of the protein and serves as a precursor molecule for the formation of Angiotensin II. Angiotensin II is the active form that causes blood vessels to constrict, resulting in increased blood pressure and fluid balance maintenance.
2. Formation: Angiotensin I is produced from angiotensinogen through the action of the renin enzyme. Angiotensin II is formed from Angiotensin I by the action of the angiotensin-converting enzyme (ACE).
3. Function: Angiotensin I does not have any biological activity, while Angiotensin II is responsible for increasing blood pressure, blood volume, and sodium levels in the body. Angiotensin II binds to several receptors throughout the body, affecting various systems and functions, including the brain, kidney, adrenal gland, vascular wall, and heart.

In summary, Angiotensin I and Angiotensin II are two different forms of angiotensins with distinct roles. Angiotensin I is an inactive precursor molecule, while Angiotensin II is the active form responsible for increasing blood pressure and maintaining fluid balance in the body.

Comparative Table: Angiotensin 1 vs 2

Angiotensin I and Angiotensin II are both peptide hormones involved in the renin-angiotensin system (RAS), which plays a crucial role in regulating blood pressure and overall cardiovascular function. Here is a table highlighting the differences between Angiotensin I and Angiotensin II:

Overall, the main difference between Angiotensin I and Angiotensin II is that Angiotensin I serves as a precursor to Angiotensin II, while Angiotensin II exerts its effects primarily through constriction of blood vessels and regulation of the neovascularization process.