What is the Difference Between Annulus Fibrosus and Nucleus Pulposus?
🆚 Go to Comparative Table 🆚The annulus fibrosus and nucleus pulposus are two distinct components of an intervertebral disc. They differ in structure, composition, and function. Here are the key differences between them:
- Structure:
- Annulus fibrosus: The outer portion of the disc, composed of layers of collagen and proteins called lamellae. The fibers of the lamellae slant at 30-degree angles, and the fibers of each lamella run in a direction opposite the adjacent layers, creating a strong and flexible structure.
- Nucleus pulposus: The inner gel-like material surrounded by the annulus fibrosus, making up about 40% of the disc. It is contained within the lamellae and composed primarily of loose collagen fibers, water, and proteins.
- Composition:
- Annulus fibrosus: Primarily composed of layers of collagen fibers, with the outer annulus containing mostly type I collagen and the inner annulus predominantly type II collagen.
- Nucleus pulposus: Composed of loose collagen fibers, water, and proteins. The water content of the nucleus is about 90% at birth and decreases to about 70% by adulthood.
- Function:
- Annulus fibrosus: Enhances the spine's rotational stability and helps resist compressive stress. It also provides a shock-absorbing effect within the spine and prevents the vertebrae from grinding against each other.
- Nucleus pulposus: Transmits stress and weight from vertebra to vertebra, along with the annulus fibrosus. It also contributes to the overall shock-absorbing effect of the intervertebral disc.
In summary, the annulus fibrosus is the outer, fibrous portion of the intervertebral disc, while the nucleus pulposus is the inner, gel-like component. The annulus fibrosus provides structure and stability to the disc, whereas the nucleus pulposus contributes to the shock-absorbing function of the disc and transmits stress and weight between vertebrae.
Comparative Table: Annulus Fibrosus vs Nucleus Pulposus
The annulus fibrosus and nucleus pulposus are two distinct components of the intervertebral disc, which is situated between the spaces of two vertebrae in the vertebral column. The annulus fibrosus is the outer portion of the intervertebral disc, while the nucleus pulposus is the inner portion. Here is a table summarizing their differences:
Feature | Annulus Fibrosus | Nucleus Pulposus |
---|---|---|
Composition | Collagen and proteins, forming layers of lamellae | Gel material |
Layers | Consists of concentric layers of collagen fibers, called lamellae | Composed of 15-25 layers of collagen |
Collagen Types | Outer annulus: mostly type I collagen; Inner annulus: predominantly type II collagen | |
Proteoglycans | Inner annulus has more proteoglycans than the outer annulus | |
Function | Provides mechanical strength and integrity to the intervertebral disc | Provides shock absorption properties and prevents bone-to-bone contact |
Shock Absorption | Not specifically designed for shock absorption | Plays a major role in providing shock absorption properties to the spine |
Innervation | Innervated in the outer few millimeters of the annulus fibrosus | |
Maturation | Annulus fibrosus cells originate from the mesenchyme during embryonic development | Nucleus pulposus cells originate from the notochord, and at age 10, notochordal cells are replaced by mature cells |
These two components of the intervertebral disc work together to provide support, shock absorption, and protection to the spine. The annulus fibrosus provides mechanical strength, while the nucleus pulposus contributes to shock absorption and prevents the vertebrae from grinding against each other.
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