What is the Difference Between Basophil and Eosinophil?
🆚 Go to Comparative Table 🆚Basophils and eosinophils are both types of white blood cells, specifically granulocytes, that play a role in the body's immune response. However, they have distinct characteristics and functions:
Basophils:
- Have an S-shaped multi-lobed nucleus.
- Cytoplasm stains blue in basic stains.
- Make up 0.5% or less of leukocytes.
- Act to initiate an inflammatory response in the body.
- Are the predominant source of IL-4 in allergen- and helminth parasite-activated PBMCs.
- Have a role in antigen presentation for helminth infection.
Eosinophils:
- Have a two-lobed nucleus.
- Cytoplasm stains red in acid stains.
- Make up 1-5% of leukocytes.
- Provide an important defense against parasites by phagocytosis and produce antihistamines.
- Produce cytotoxic granule proteins as their major effector function.
- Express a range of cytokines, but IL-5 is specific for eosinophil development and differentiation.
In summary, basophils are involved in initiating inflammatory responses, while eosinophils play a crucial role in defending against parasites and producing antihistamines. They have different nucleus shapes and staining colors, and their abundance in leukocytes varies.
Comparative Table: Basophil vs Eosinophil
Basophils and eosinophils are both types of white blood cells (leukocytes) that play roles in the immune system. Here are the main differences between them:
Feature | Basophils | Eosinophils |
---|---|---|
Function | Initiate an inflammatory response in the body | Effective against larger parasites |
Production | Produced against myeloid cells in the bone marrow | Produced from myeloid cells in the bone marrow |
Nucleus | Bilobed and S-shaped | Bilobed and sausage-shaped |
Granules | Basic | Acidic |
Allergen Response | Acts against allergens |
Both basophils and eosinophils are granulocytes, which means they have granules in their cytoplasm that contain various enzymes and proteins. These granules play a role in the cells' function in the immune response.
- Mast Cell vs Basophil
- Hematoxylin vs Eosin
- Acidophilic vs Basophilic
- Neutrophils vs Lymphocytes
- Granulocytes vs Agranulocytes
- Monocyte vs Lymphocyte
- Atopic Dermatitis vs Eczema
- Eczema vs Hives
- Lymphocytes vs Macrophages
- Eczema vs Dermatitis
- Eczema vs Psoriasis
- IgG vs IgE
- Phagocytes vs Lymphocytes
- B Cells vs Plasma Cells
- Myeloid vs Lymphoid Cells
- Lymphocyte vs Lymphoblast
- Leukocytosis vs Lymphocytosis
- Leukocytes vs Lymphocytes
- Lymphocytes vs Leucocytes