What is the Difference Between Cetirizine Hydrochloride and Levocetirizine Dihydrochloride?
🆚 Go to Comparative Table 🆚Cetirizine hydrochloride and levocetirizine dihydrochloride are both antihistamines used to treat allergy symptoms, but they have some differences in their chemical structure and side effects:
- Chemical Structure: Levocetirizine is the active enantiomer of cetirizine, meaning that it is a mirror image of cetirizine. This slight difference in chemical structure results in some variations in their side effects and effectiveness.
- Drowsiness: The key difference between the two antihistamines is their likelihood to cause drowsiness. Both medications are classified as non-sedating, but levocetirizine (Xyzal) is slightly less likely to cause drowsiness compared to cetirizine (Zyrtec).
- Effectiveness: Since both medications have a common core chemical structure, Zyrtec and Xyzal generally have the same level of effectiveness and range of allergy symptoms treated.
- Price: Xyzal is often more expensive than Zyrtec, as it is considered less sedating and a newer medication.
Overall, both cetirizine and levocetirizine are effective in treating allergy symptoms, but their differences in chemical structure and side effects may influence a person's preference for one medication over the other. It is essential to consult with a healthcare professional to determine the most suitable medication for your specific needs.
Comparative Table: Cetirizine Hydrochloride vs Levocetirizine Dihydrochloride
Cetirizine hydrochloride and levocetirizine dihydrochloride are both antihistamines used to treat allergy symptoms such as itching, runny nose, and watery eyes. Here is a comparison table highlighting the differences between the two medications:
Property | Cetirizine Hydrochloride | Levocetirizine Dihydrochloride |
---|---|---|
Generation | Second-generation | Third-generation |
Bioavailability | About 70% | Unspecified |
Protein Binding | 88% to 96% | Unspecified |
Metabolism | Minimal | Unspecified |
Onset of Action | 20-42 minutes | Unspecified |
Elimination Half-life | 6.5-10 hours | 6-10 hours |
Duration of Action | 24 hours | Unspecified |
Excretion | Urine and feces | Kidney and fecal |
Cetirizine hydrochloride is sold under the name Zyrtec, while levocetirizine dihydrochloride is sold under the name Xyzal. Both medications are effective in treating allergy symptoms, but they have some differences in their absorption, protein binding, and elimination half-life.
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