What is the Difference Between Cyanocobalamin and Hydroxocobalamin?

Cyanocobalamin and Hydroxocobalamin are two forms of Vitamin B12, which is an essential nutrient for various bodily functions. The main differences between them are their chemical structure, bioavailability, and use cases.

Cyanocobalamin

• Cyanocobalamin is a synthetic form of Vitamin B12 and is the most common and cost-effective form found in supplements and some fortified foods.
• It contains a cyanide molecule that gives it stability in products.
• The body converts Cyanocobalamin into the active forms of Vitamin B12, Methylcobalamin and Adenosylcobalamin, which are readily used by the body.
• Cyanocobalamin is generally considered safe and effective in treating cases of fatigue, stress, and low energy.

Hydroxocobalamin

• Hydroxocobalamin is a highly bioavailable form of Vitamin B12 and is used to treat people with serious deficiencies.
• It contains a hydroxyl group instead of the methyl or cyano group found in Methylcobalamin.
• Hydroxocobalamin helps reduce the unwanted amount of nitric oxide in the body, which, if not removed, can lead to a range of diseases.
• It is also used to help detoxify excess cyanide produced from smoking and polluted air, protecting against oxidative stress and inflammation.

In summary, Cyanocobalamin is a synthetic form of Vitamin B12 that is more cost-effective and often found in supplements and fortified foods, while Hydroxocobalamin is a highly bioavailable form that is used to treat more serious deficiencies and offers additional health benefits. The choice between the two forms depends on individual needs and the recommendations of a healthcare professional.

Comparative Table: Cyanocobalamin vs Hydroxocobalamin

Here is a table comparing the differences between Cyanocobalamin and Hydroxocobalamin:

Both Cyanocobalamin and Hydroxocobalamin are manufactured versions of vitamin B12, which are important in treating and preventing vitamin B12 deficiency. The key difference between the two is that Cyanocobalamin starts to act after being converted into Hydroxocobalamin, whereas Hydroxocobalamin starts to act straight away after the uptake.