What is the Difference Between GABA and PharmaGABA?

GABA (gamma-aminobutyric acid) and PharmaGABA are different forms of the neurotransmitter GABA, which plays a crucial role in controlling nervous system excitability. The key differences between GABA and PharmaGABA are:

1. Origin: GABA is a naturally occurring neurotransmitter in the central nervous system, while PharmaGABA is a synthetic form of GABA.
2. Production: PharmaGABA is produced through a fermentation process using Lactobacillus bacteria, which is a probiotic found in kimchi, making it the only natural form of GABA available.
3. Availability: GABA is an amino acid supplement and neurotransmitter, while gabapentin is a prescription medication. PharmaGABA is a synthetic form of GABA that is available as a supplement, but it is not the same as prescription GABA medications like gabapentin.
4. Effects: GABA and PharmaGABA are thought to have similar effects on the nervous system, as they both serve as inhibitory neurotransmitters. However, gabapentin is an anticonvulsant medication used to treat conditions like epilepsy and neuropathic pain.

In summary, GABA is a naturally occurring neurotransmitter, while PharmaGABA is a synthetic form of GABA produced through fermentation. They both serve as inhibitory neurotransmitters, but PharmaGABA is available as a supplement, whereas GABA medications like gabapentin are available only by prescription.

Comparative Table: GABA vs PharmaGABA

GABA (gamma-aminobutyric acid) and PharmaGABA are related but distinct compounds. GABA is the major inhibitory neurotransmitter in the central nervous system, while PharmaGABA is a form of GABA produced via industrial fermentation of the amino acid glutamic acid using beneficial bacteria. Here is a table comparing the differences between GABA and PharmaGABA:

It is essential to note that GABA and PharmaGABA are different from gabapentin, an anticonvulsant medication that is a structural derivative of GABA. Gabapentin is not included in the table as it is a distinct compound with a different mechanism of action.