What is the Difference Between Genotype and Blood Group?

The main difference between genotype and blood group lies in their definition and composition. Here are the key differences between the two:

• Genotype: The genotype represents the genetic makeup of a cell, including DNA sequences that are inherited from both parents. It is a factor that determines the physical appearance or phenotype of a person. For example, in humans, there are six different genotypes based on the type of hemoglobin found in red blood cells (RBCs): AA, AC, AS, CC, SC, and SS. Individuals with genotypes SS and SC are prone to sickle cell diseases.
• Blood Group: Blood groups refer to the different types of blood found in humans, which are determined by various antigens found on the surface of RBCs. In humans, there are four main blood groups (A, B, AB, and O), and eight different phenotypes, including A-Positive, B-Positive, A-Negative, B-Negative, AB-Positive, AB-Negative, O-Positive, and O-Negative. Blood groups are determined by proteins or antigens situated on the surface of a red blood cell.

In summary, genotypes are about the genetic makeup inside every cell, while blood groups are about the antigens found on the surface of red blood cells.

Comparative Table: Genotype vs Blood Group

The main difference between genotype and blood group is that genotype is the genetic makeup of a cell, while blood group refers to the different types of blood found in humans, determined by the antigens on the surface of red blood cells. Here is a table comparing the differences between genotype and blood group:

In summary, genotype is the genetic makeup of a cell and determines the phenotype of a person, while blood group is determined by the antigens on the surface of red blood cells. These two factors are used to categorize and differentiate humans based on their genetic and physical traits.