What is the Difference Between Granulocytes and Agranulocytes?

Granulocytes and agranulocytes are two types of white blood cells that play crucial roles in the immune system. The main differences between them are:

1. Origin: Granulocytes originate from the bone marrow, while agranulocytes originate from the lymph nodes.
2. Cytoplasm: Granulocytes contain granules in their cytoplasm, which contain enzymes that help fight infections. Agranulocytes, on the other hand, do not have granules in their cytoplasm.
3. Nucleus: Granulocytes have a lobed nucleus with multiple segments, while agranulocytes have a single-lobed nucleus.
4. Types: Granulocytes include basophils, neutrophils, eosinophils, and mast cells. Agranulocytes consist of monocytes, lymphocytes, and macrophages.
5. Percentage in Leukocytes: Granulocytes make up about 65% of white blood cells, while agranulocytes make up the remaining 35%.
6. Function: Granulocytes are involved in innate immunity, providing a general response to infections. Agranulocytes, particularly lymphocytes, are involved in adaptive immunity, helping to recognize antigens, produce antibodies, and destroy cells that can cause damage to the body. Macrophages, another type of agranulocyte, locate and destroy foreign bodies by engulfing them.

Comparative Table: Granulocytes vs Agranulocytes

Granulocytes and agranulocytes are two types of white blood cells that play crucial roles in the immune system. Here is a table comparing their differences:

Granulocytes are white blood cells that contain granules in their cytoplasm and have a lobed nucleus. They originate from the bone marrow and are responsible for innate immunity. The most abundant granulocytes are neutrophils, which make up around 70% of white blood cells.

Agranulocytes, on the other hand, do not contain granules in their cytoplasm and have a single lobe nucleus. They originate from the lymph nodes and are responsible for both innate and adaptive immunity. Examples of agranulocytes include lymphocytes, macrophages, and monocytes.