What is the Difference Between Hepatic Bile and Gallbladder Bile?

Hepatic bile and gallbladder bile are both components of the biliary system, which is responsible for producing, storing, and releasing bile to aid in the digestion of food. The main differences between hepatic bile and gallbladder bile are:

1. Origin and storage: Hepatic bile is produced in the liver, while gallbladder bile is stored in the gallbladder, a small, pear-shaped, muscular storage sac. Bile flows from the liver, through the hepatic ducts, into the cystic duct, and to the gallbladder, where it is stored.
2. Composition: Hepatic bile and gallbladder bile have different compositions. Gallbladder bile, but not hepatic bile, of animals or patients with cholesterol gallstones has been reported to contain higher protein concentrations. In the gallbladder, hepatic bile is concentrated five to ten times by active absorption of water and electrolytes.
3. Release: When bile is needed for digestion, the gallbladder contracts and releases bile into the cystic duct, which then flows into the common bile duct and empties into the first part of the small intestine.

In summary, hepatic bile is produced in the liver and flows through the hepatic ducts to the gallbladder, where it is stored and concentrated. Gallbladder bile has a different composition than hepatic bile and is released when needed for digestion.

Comparative Table: Hepatic Bile vs Gallbladder Bile

The main difference between hepatic bile and gallbladder bile lies in their production and storage. Hepatic bile is produced continuously by the liver, while gallbladder bile is stored and concentrated in the gallbladder until it is needed for digestion. Here is a table highlighting the differences between hepatic bile and gallbladder bile:

In summary, hepatic bile is produced by the liver and flows directly into the small intestine, while gallbladder bile is stored in the gallbladder and released when needed for digestion. Hepatic bile is alkaline, whereas gallbladder bile is acidic.