What is the Difference Between Linkage and Recombination?
🆚 Go to Comparative Table 🆚Linkage and recombination are two phenomena involved in the inheritance of genes. They differ in the way genes are inherited and the genetic material is exchanged between organisms.
Linkage:
- Refers to the inheritance of two or more DNA segments as they reside in the same chromosome.
- Genes are inherited together most of the time.
- Linkage helps to keep the genes together in the same chromosome.
- The linkage between two genes weakens as the distance between them grows.
- There are two types of linkages: Complete Linkage (due to the lack of crossing over, genes on the same chromosome do not split and are inherited together over generations) and Incomplete Linkage (genes on separate chromosomes are never linked).
Recombination:
- Occurs when DNA segments separate during crossing over in meiosis.
- Results in the formation of an offspring with combined traits.
- Generation of genetic variety at the gene level originates from this recombination process.
- Recombination is the exchange of genetic material between different organisms, leading to the production of offsprings with the combination of traits.
- There are two types of recombination: Homologous recombination (nucleotide sequences are exchanged between homologous chromosomes) and Non-homologous recombination (chromosomal double-strand breaks are repaired by the exchange of genetic material between two chromosomes that are not homologous).
In summary, linkage refers to the inheritance of genes that are close together on the same chromosome, while recombination is the process where DNA segments separate during crossing over in meiosis, leading to the production of offsprings with combined traits.
Comparative Table: Linkage vs Recombination
Based on the search results, here is a table summarizing the differences between linkage and recombination:
Feature | Linkage | Recombination |
---|---|---|
Definition | Linkage refers to the inheritance of two or more DNA segments as they reside in the same chromosome for more than two generations. | Recombination is the process where DNA segments separate during crossing over in meiosis, resulting in the formation of an offspring with combined parental qualities. |
Purpose | Linkage helps to keep the genes together in the same chromosome. | Recombination leads to genetic diversity at the gene level by creating new allele combinations. |
Types | Complete Linkage: due to the lack of crossing over, genes on the same chromosome do not split and are inherited together over generations. | There are three types of recombination: homologous, site-specific, and non-homologous. |
Recombination Frequency | The test cross progeny's recombination frequency is never greater than 50%. | The chromosomal theory of inheritance came into existence long after Mendelian genetics. |
Linkage is responsible for keeping genes together in the same chromosome, while recombination is the process that creates new allele combinations, leading to genetic diversity at the gene level.
- Complementation vs Recombination
- Mutation vs Recombination
- Recombination vs Crossing Over
- Linkage vs Crossing Over
- Homologous Recombination vs Site-Specific Recombination
- Homologous Recombination vs Non-homologous Recombination
- Crossover Frequency vs Recombination Frequency
- Genetic Linkage vs Linkage Disequilibrium
- Interchromosomal vs Intrachromosomal Recombination
- Genetic Map vs Linkage Map
- Recombinant vs Nonrecombinant
- Transformants vs Recombinants
- Translocation vs Crossing Over
- Monohybrid Cross vs Reciprocal Cross
- Linked vs Unlinked Genes
- Synapsis vs Crossing Over
- Parental Type vs Recombinant Type Chromosomes
- Genetic Engineering vs Recombinant DNA Technology
- Hybridization vs Cross Breeding