What is the Difference Between Nullisomy and Double Monosomy?
🆚 Go to Comparative Table 🆚Nullisomy and double monosomy are both aneuploidy conditions, which are abnormal changes in the number of chromosomes in a cell. They differ in the number of chromosomes lost in each case.
- Nullisomy: In nullisomy, both chromosomes in a pair of homologous chromosomes are missing. This results in a chromosomal composition of 2n-2. Nullisomy is a condition where individuals are called nullisomics.
- Double Monosomy: In double monosomy, one chromosome from each of two pairs of homologous chromosomes is missing. This results in a chromosomal composition of 2n-1-1.
In summary, the main difference between nullisomy and double monosomy is the number of chromosomes lost in each condition:
- In nullisomy, both chromosomes of a homologous chromosome pair are missing (2n-2).
- In double monosomy, one chromosome from each of two pairs of homologous chromosomes is missing (2n-1-1).
On this pageWhat is the Difference Between Nullisomy and Double Monosomy? Comparative Table: Nullisomy vs Double Monosomy
Comparative Table: Nullisomy vs Double Monosomy
Here is a table summarizing the differences between nullisomy and double monosomy:
Feature | Nullisomy | Double Monosomy |
---|---|---|
Definition | Loss of both chromosomes in a pair of homologous chromosomes. | Loss of one chromosome from each of two pairs of homologous chromosomes. |
Representation | 2n-2. | 2n-1-1. |
Type of Aneuploidy | Both chromosomes of a homologous chromosome pair are missing. | One chromosome from each of two pairs of homologous chromosomes is missing. |
Occurrence | Rare. | Rare. |
Both nullisomy and double monosomy are types of aneuploidy, which is a mutation in which the chromosomal number is abnormal, changing the total number of chromosomes in a set. They produce abnormal chromosome numbers and disrupt the overall gene balance in the chromosome set.
Read more:
- Monosomy vs Trisomy
- Trisomy vs Triploidy
- Monozygotic vs Dizygotic Twins
- Mosaicism vs Uniparental Disomy
- Monospermy vs Polyspermy
- Compound Heterozygote vs Double Heterozygote
- Homozygous vs Heterozygous
- Nondisjunction in Meiosis 1 vs 2
- Homozygous vs Hemizygous
- Nondisjunction vs Translocation Mutations
- Twins vs Identical Twins
- Twins vs Identical Twins
- Uniparental Disomy vs Genomic Imprinting
- Monogenic Disorders vs Chromosomal Disorders
- Aneuploidy vs Polyploidy
- Mosaic Down Syndrome vs Down Syndrome
- Haploid vs Diploid
- Deletion vs Duplication of Chromosome
- Euploidy vs Aneuploidy