What is the Difference Between PEP and PrEP?

PrEP and PEP are two methods used to prevent HIV infection using anti-HIV medications. However, they are used in different situations and serve distinct purposes:

• PrEP (Pre-Exposure Prophylaxis): PrEP is for people who don't already have HIV but are at risk of getting it. It is taken before potential exposure to HIV to reduce the risk of infection. PrEP can be in the form of a daily pill or an injection every two months. If exposed to HIV, the medicine can stop the virus from taking hold and spreading throughout the body.
• PEP (Post-Exposure Prophylaxis): PEP is for people who have possibly been exposed to HIV and is used only in emergency situations. It must be started within 72 hours after a possible exposure to HIV. PEP is a four-week course of drugs, taken once a day during that time. If taken within 24 hours of exposure to HIV, PEP can significantly reduce the risk of infection.

In summary, the main difference between PrEP and PEP is that PrEP is taken before potential exposure to HIV to prevent infection, while PEP is taken after possible exposure to HIV to reduce the risk of infection.

Comparative Table: PEP vs PrEP

Here is a table comparing the differences between PrEP and PEP:

Both PrEP and PEP are treatment plans intended for people at high risk of HIV transmission but are currently negative for the virus. PrEP is designed for pre-exposure to HIV and is taken continuously to prevent infection, while PEP is used after potential exposure and involves a one-time, 28-day course of treatment. The medications used for both treatments include Truvada, but PEP requires an additional drug due to its different mechanism of action.