What is the Difference Between Periosteal and Parosteal Osteosarcoma?
🆚 Go to Comparative Table 🆚The main differences between periosteal and parosteal osteosarcoma are their origins, radiological features, histological grade, and prognosis. Here are the key differences:
- Origin: Periosteal osteosarcoma arises from under the periosteum, while parosteal osteosarcoma arises on the surface of the bone.
- Radiological Features: Periosteal osteosarcoma typically presents with periosteal elevation, while parosteal osteosarcoma has a densely ossified mass radiologically.
- Histological Grade: Periosteal osteosarcoma is of intermediate grade, while parosteal osteosarcoma is well-differentiated (Grade 1 or 2).
- Prognosis: Periosteal osteosarcoma has a better prognosis than conventional osteosarcoma but not as good as parosteal osteosarcoma. Parosteal osteosarcoma has a low-grade histological picture and is considered a slow-growing tumor.
In summary, periosteal osteosarcoma arises from under the periosteum, has an intermediate histological grade, and a better prognosis than conventional osteosarcoma. In contrast, parosteal osteosarcoma arises on the surface of the bone, has a well-differentiated histological grade, and a more favorable prognosis.
On this pageWhat is the Difference Between Periosteal and Parosteal Osteosarcoma? Comparative Table: Periosteal vs Parosteal Osteosarcoma
Comparative Table: Periosteal vs Parosteal Osteosarcoma
Here is a table comparing the differences between periosteal and parosteal osteosarcoma:
Feature | Periosteal Osteosarcoma | Parosteal Osteosarcoma |
---|---|---|
Definition | A high-grade osteosarcoma that arises from the periosteum below the surface of the bone | A low-grade osteosarcoma that arises from the periosseous tissues adjacent to the cortex |
Age of Onset | Tends to occur at a younger age, with a mean age of 20 years in one study | Generally affects younger patients, often in their 20s |
Radiological Appearance | Characterized by periosteal elevation and nonhomogeneous calcified spiculations perpendicular to the cortex, giving a "sunburst appearance" | Rarely presents with periosteal elevation |
Histological Grade | Intermediate or higher-grade osteosarcoma | Lower-grade osteosarcoma |
Treatment | Wide resection with limb salvage is the surgical treatment of choice | Chemotherapy and radiotherapy are generally not very effective |
Please note that these are general characteristics and may not apply to every case of periosteal or parosteal osteosarcoma.
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