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Guilherme Mazui

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What is the Difference Between Protomers and Capsomeres?

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The main difference between protomers and capsomeres lies in their role and structure within the viral capsid:

  • Protomers: These are structural units of oligomeric proteins, meaning they are composed of more than one polypeptide chain (chain of amino acids that make up proteins). Protomers aggregate to form capsomeres.
  • Capsomeres: These are individual proteins composed of protomers and serve as protein subunits of the viral capsid. Capsomeres are the building blocks of the capsid, while protomers are the subunits that make up capsomeres. Capsomeres aggregate to form the capsid, a protein coat that surrounds and protects the viral genome.

In summary, protomers are subunits of capsomeres, and capsomeres are subunits of the viral capsid. Both protomers and capsomeres can self-assemble.

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  • What is the Difference Between Protomers and Capsomeres?
  • Comparative Table: Protomers vs Capsomeres

    • Comparative Table: Protomers vs Capsomeres

    Here is a table summarizing the differences between protomers and capsomeres:

    Feature Protomers Capsomeres
    Definition Protomers are subunits of capsomeres and the structural units of oligomeric proteins. Capsomeres are protein subunits of the viral capsid, formed by the aggregation of protomers.
    Self-assembly Protomers connect with each other via specific bonds and self-assemble. Capsomeres self-assemble to form the capsid, which is the protein coat that surrounds and protects the viral genome.
    Function Protomers are the functional units of the capsid. Capsomeres are the morphological units of the capsid and can be arranged in different ways (helical, icosahedral, or complex) depending on the virus.
    Structure Protomers are composed of several different polypeptide chains. Capsomeres are composed of several protomers and are the building blocks of the capsid.

    In summary, protomers are the subunits that make up capsomeres, which in turn form the viral capsid. Protomers self-assemble to create capsomeres, and capsomeres self-assemble to form the capsid, providing structure and protection to the viral genome.

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    Guilherme Mazui

    Guilherme Mazui is graduated in journalism from the Federal University of Minas Gerais (UFMG) and a master's degree in Communication from the University of São Paulo (USP). In addition, he has experience in advertising writing and has worked as a content editor in several companies.