What is the Difference Between PUPPP and Cholestasis?
🆚 Go to Comparative Table 🆚PUPPP (Pruritic Urticarial Papules and Plaques of Pregnancy) and cholestasis (Intrahepatic Cholestasis of Pregnancy) are two distinct medical conditions that can occur during pregnancy, causing itching. However, they have different characteristics and causes:
PUPPP:
- Causes an extremely irritating hive-like rash, typically occurring in the stretch marks on the abdomen.
- Risk factors include being white, carrying a male fetus, being the first pregnancy, and carrying twins or triplets.
- Caused by stretching and hormone changes during pregnancy.
Cholestasis:
- Causes the slowing of bile flow through the biliary system.
- Risk factors include personal or family history, history of liver damage or disease, being pregnant with multiple babies, and pregnancy at an older age (such as 35).
- Caused by a problem with the liver that inhibits its ability to secrete bile.
In summary, while both PUPPP and cholestasis can cause itching during pregnancy, they are different medical conditions with distinct causes and characteristics. PUPPP is associated with a hive-like rash, while cholestasis is associated with the slowing of bile flow through the biliary system.
Comparative Table: PUPPP vs Cholestasis
PUPPP (Pruritic Urticarial Papules and Plaques of Pregnancy) and cholestasis are two distinct medical conditions that can occur during pregnancy. They share some similarities, such as causing itching, but they have different characteristics and risk factors. Here is a table summarizing the differences between PUPPP and cholestasis:
Characteristic | PUPPP | Cholestasis |
---|---|---|
Definition | A condition causing an extremely irritating hive-like rash. | A condition causing the slowing of bile flow through the biliary system. |
Risk Factors | White race, male fetus, first pregnancy, carrying twins or triplets. | Personal or family history, liver damage or disease (hepatitis C, gallbladder stones), multiple babies, pregnancy at an older age (35+). |
Symptoms | Itching, hive-like rash. | Itching without a rash, may be accompanied by jaundice. |
Location | Rash typically begins on the abdomen and spreads to the chest, legs, and arms. | Pruritus usually begins on the palms and soles and may become more widespread. |
Treatment | Topical steroids, oral antihistamines. | Treatment varies depending on the severity of the condition, may include medications to improve bile flow or treat underlying liver disease. |
It is essential to consult a healthcare professional for proper diagnosis and treatment if you experience symptoms of either PUPPP or cholestasis during pregnancy.
- Intrahepatic vs Extrahepatic Cholestasis
- Cholangitis vs Cholecystitis
- Gallstones vs Cholecystitis
- Biliary Colic vs Cholecystitis
- Cholecystitis vs Cholelithiasis
- Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis
- Jaundice vs Hepatitis
- Cirrhosis vs Hepatitis
- PP vs PPCP
- Hyperlipidemia vs Hypercholesterolemia
- Fatty Liver vs Cirrhosis
- Physiological vs Pathological Jaundice
- Hepatocellular vs Obstructive Jaundice
- Hypercholesterolemia vs Dyslipidemia
- Cystic Fibrosis vs Pulmonary Fibrosis
- Papules vs Pustules
- Hepatic Bile vs Gallbladder Bile
- Icterus vs Jaundice
- Cholesterol vs Cholesteryl Ester