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Guilherme Mazui

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What is the Difference Between Transformation and Transduction?

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Transformation and transduction are two processes that can be used to transfer DNA from one bacterial cell to another. Here are the main differences between them:

Transformation:

  • Involves the uptake of a piece of DNA floating in the environment by a bacterium.
  • Doesn't require any antibiotic resistance.
  • The transfer of DNA from the bacteria to the chromosome of the recipient doesn't require a virus as an intermediary.
  • Plasmid transfer is possible.
  • Transformation is susceptible to DNase.

Transduction:

  • DNA is accidentally moved from one bacterium to another by a virus.
  • Requires the presence of bacteriophage.
  • The transfer of DNA from the bacteria to the chromosome of the recipient requires a virus as an intermediary.
  • Plasmid transfer is not possible.
  • Transduction is resistant to DNase.

Both transformation and transduction are involved in horizontal gene transfer from one bacterium to another and were discovered through studies on bacterial conjugation, transformation, and transduction.

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  • What is the Difference Between Transformation and Transduction?
  • Comparative Table: Transformation vs Transduction

    • Comparative Table: Transformation vs Transduction

    Transformation and transduction are two main processes that can be used to transfer DNA matter from one bacterial cell to another. Here is a table highlighting the differences between the two processes:

    Transformation Transduction
    DNA fragments from a bacterium are passed and incorporated into the recipient’s chromosomes. The transfer of DNA from the bacteria to the chromosome of the recipient requires a virus as an intermediary.
    It doesn't require the presence of bacteriophage. It requires the presence of bacteriophage.
    It doesn't require any antibiotic resistance. It requires antibiotic resistance.
    Plasmid transfer is possible. Plasmid transfer is not possible.
    Naked DNA fragments move through the walls or membrane of the recipient. DNA is accidentally moved from one bacterium to another by a virus.
    It occurs through lytic or lysogenic cycles. It was discovered by Fred Griffith in 1928.
    It was discovered by Norton Zinder and Joshua Lederberg in 1952.
    Transformation is susceptible to DNase. Transduction is resistant to DNase.

    Both transformation and transduction are involved in horizontal gene transfer from one bacterium to another.

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    Guilherme Mazui

    Guilherme Mazui is graduated in journalism from the Federal University of Minas Gerais (UFMG) and a master's degree in Communication from the University of São Paulo (USP). In addition, he has experience in advertising writing and has worked as a content editor in several companies.