What is the Difference Between Ubiquitination and SUMOylation?
🆚 Go to Comparative Table 🆚Ubiquitination and SUMOylation are two important post-translational modifications that
On this pageWhat is the Difference Between Ubiquitination and SUMOylation? Comparative Table: Ubiquitination vs SUMOylation
Comparative Table: Ubiquitination vs SUMOylation
The main differences between ubiquitination and SUMOylation are their functions and the type of proteins they target. Here is a table comparing the two post-translational modifications:
Feature | Ubiquitination | SUMOylation |
---|---|---|
Function | Marks proteins for degradation | Does not mark proteins for degradation; regulates protein localization and activity |
Target Proteins | Regulates thousands of proteins | Targets specific proteins involved in various cellular processes |
Enzyme Classes | Uses different enzyme classes | Analogous to ubiquitination in terms of reaction scheme and enzyme classes used |
Reversibility | Reversible process | Reversible process |
Ubiquitination is a post-translational modification that marks proteins for degradation, while SUMOylation does not mark proteins for degradation but instead regulates protein localization and activity. Both modifications are reversible processes that involve enzyme classes. Although SUMOylation is analogous to ubiquitination in terms of reaction scheme and enzyme classes used, they differ in their functions and the type of proteins they target.
Read more:
- Glycosylation vs Glycosidation
- Post Transcriptional vs Post Translational Modification
- Glycation vs Glycosylation
- Ubiquinones vs Cytochromes
- Acetylation vs Methylation
- Ubiquinone vs Ubiquinol
- Summary vs Summation
- Acetylation vs Acylation
- Integration vs Summation
- Ubiquinone vs Plastoquinone
- Co vs Post Translational Modification
- N Glycosylation vs O Glycosylation
- Ubiquinol vs CoQ10
- DNA Sequence Mutations vs Epigenetic Modifications
- Phosphorylation vs Dephosphorylation
- DNA Methylation vs Histone Acetylation
- Proteomics vs Metabolomics
- Proteomics vs Transcriptomics
- Substrate Level Phosphorylation vs Oxidative Phosphorylation