What is the Difference Between VNTR and Probe?
🆚 Go to Comparative Table 🆚The main difference between VNTR and probe lies in their origin and function:
VNTR (Variable Number Tandem Repeat):
- VNTR is a short nucleotide sequence organized in tandem repeats in the genome.
- They are naturally occurring in the genome and can be found on many chromosomes.
- VNTRs often show variations in length between individuals and are used in genetics, biology research, forensics, and DNA fingerprinting.
- They are small DNA fragments, 15-100 base pairs in length, found within and between genes.
Probe:
- A probe is an artificially synthesized short DNA or RNA sequence.
- Probes can be radioactively labeled and used to detect the presence of nucleotide sequences in DNA or RNA samples.
- They are single-stranded DNA or RNA with a specific base sequence, complementary to the target sequence in the DNA sample.
- Probes are used in various molecular biological techniques, such as forensic studies and genetics.
In summary, VNTRs are naturally occurring genetic sequences with variable lengths between individuals, while probes are artificially synthesized and can be labeled radioactively to detect target nucleotide sequences.
Comparative Table: VNTR vs Probe
Here is a table comparing the differences between VNTR and Probe:
Feature | VNTR (Variable Number Tandem Repeat) | Probe |
---|---|---|
Definition | A short nucleotide sequence organized in tandem repeats in the genome. | A short, artificially synthesized DNA or RNA sequence. |
Occurrence | Naturally occurring in the genome. | Created artificially for specific purposes. |
Length | VNTRs can differ among individuals due to variations in the number of repeats. | Probes are typically around 100-1000 bases long. |
Application | Used in genetics, biology research, forensics, and DNA fingerprinting. | Used in DNA or RNA samples to detect the presence of specific nucleotide sequences. |
Detection | VNTR analysis involves PCR and electrophoresis. | Probes can be radioactively labeled for detection purposes. |
Both VNTR and probe are nucleic acids or short nucleotide sequences with immense use in different molecular biological techniques, mainly in forensic studies.
Read more:
- VNTR vs STR
- Probe vs Primer
- DNA vs RNA Probes
- Radioactive vs Nonradioactive Probes
- DNA Profiling vs DNA Sequencing
- DNA Fingerprinting vs DNA Profiling
- DNA Profiling vs Genetic Screening
- SNP vs RFLP
- Prophage vs Provirus
- Gene Sequencing vs DNA Fingerprinting
- VDRL vs RPR
- RAPD vs RFLP
- PCR vs DNA Sequencing
- NAAT vs PCR
- Gene Cloning vs PCR
- SNP vs Mutation
- Mole vs Vole
- Plasmid vs Transposon
- Genotyping vs Sequencing