What is the Difference Between Fischer Projection and Haworth Projection?
🆚 Go to Comparative Table 🆚The main difference between Fischer projection and Haworth projection lies in the type of molecular structures they represent.
- Fischer Projection: This is a 2D representation of an organic molecule by projection, used primarily for sugars in their open-chain form. It is useful for analyzing diastereomeric sugar structures, as the eye can quickly identify stereochemical differences.
- Haworth Projection: This is a way of drawing the structure of an organic molecule representing the cyclic form of the molecule. It is often used to depict sugars in their cyclic forms. Although a Haworth projection is a convenient way to show stereochemistry, it does not provide a realistic depiction of conformation. To show both conformation and stereochemistry, the ring must be drawn in the chair form.
In summary, Fischer projections are used for sugars in their open-chain form, while Haworth projections are used to depict sugars in their cyclic forms.
Comparative Table: Fischer Projection vs Haworth Projection
Fischer projections and Haworth projections are both used to represent carbohydrates, but they differ in the way they depict the molecules' structures. Here is a comparison between the two:
Feature | Fischer Projection | Haworth Projection |
---|---|---|
Form | Open-chain | Cyclic |
Projection Type | 2D representation | 3D representation |
Carbohydrates | Primarily used | Primarily used |
Stereochemistry | Yes | Yes |
Drawing Convention | Carbons and hydrogens shown, usually in a 'zigzag' style | Hydrogens implicit on carbons, thicker lines for closer atoms |
Fischer projections are used for sugars in their open-chain form, while Haworth projections are often used to depict sugars in their cyclic forms. Although a Haworth projection is a convenient way to show stereochemistry, it does not provide a realistic depiction of conformation. To show both conformation and stereochemistry, the ring must be drawn in the chair form.
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