What is the Difference Between Niacin and Niacinamide?

Niacin and niacinamide are both forms of vitamin B3, but they have different chemical structures and specific health applications when used in higher doses.

• Niacin: Also known as nicotinic acid, niacin is found in fresh meat, yeast, and other food sources. It is often taken to support cholesterol levels already within the healthy range (both LDL and HDL). High doses of niacin can cause flushing, a condition that causes blood vessels to widen, leading to red and itchy skin.
• Niacinamide: Also known as nicotinamide or nicotinic acid amide, niacinamide is derived from niacin and can be made by the human body from niacin. It is found in meat, liver, fish, whole wheat, and eggs. Niacinamide does not cause the flushing effect associated with high doses of niacin. It is used to promote a healthy insulin response, maintain joint health, and support brain function, but does not support cholesterol balance.

In summary, while both niacin and niacinamide are forms of vitamin B3, they have distinct properties and effects on the body. Niacin is typically used for cholesterol support, while niacinamide is used for various health benefits such as insulin response, joint health, and brain function.

Comparative Table: Niacin vs Niacinamide

Niacin and niacinamide are both forms of vitamin B3, but they have different properties and effects on the body. Here is a table highlighting the differences between the two:

Niacin is an essential human nutrient and is sometimes referred to as vitamin B3. It is derived from tryptophan, an amino acid, and can also be made in the body. Niacinamide, on the other hand, is derived from niacin and is converted to niacinamide in the body. Niacinamide is more similar to NAD, which results in greater bioavailability and fewer side effects.

In summary, niacin and niacinamide both provide the benefits of vitamin B3, but niacinamide has a different molecular structure that allows it to bypass the step causing flushing, making it a preferred choice for those sensitive to niacin's effects.